Ivanovic reached her first grand slam singles quarterfinal at the 2005 French Open, defeating third seed Amélie Mauresmo en route before losing in straight sets to seventh seed, Nadia Petrova. The following year, Ivanovic won her first major title at the 2006 Rogers Cup, defeating former World No. 1Martina Hingis in the final in straight sets. Ivanovic subsequently won the US Open Series that year.
In May 2007, Ivanovic cracked the top ten of the WTA Rankings for the first time in her career, rising to a then career high of World No. 8 after winning the Qatar Telecom German Open by defeating World No. 4 Svetlana Kuznetsova in three sets in the final. At the 2007 French Open, Ivanovic reached her first grand slam singles final, defeating Kuznetsova in the quarterfinals and World No. 2 Maria Sharapova in the semi-finals before losing in straight sets to World No. 1 and two-time defending champion Justine Henin in the final. At the 2007 Wimbledon Championships, Ivanovic reached her second consecutive grand slam singles semi-final but lost in straight sets to the eventual champion, Venus Williams. Later that year, Ivanovic won her fourth career singles title at the East West Bank Classic and as a result, achieved a new career high singles ranking of World No. 4. Ivanovic's results throughout the year allowed her to qualify for the year-ending WTA Tour Championships for the first time in her career. She progressed to the semi-finals where she lost in straight sets to the World No. 1 Justine Henin. Ivanovic finished the year ranked World No. 4, which remains her best finish to date.
In January 2008, Ivanovic reached her first Australian Open final and second grand slam singles final overall but lost in straight sets to Maria Sharapova. However, Ivanovic achieved a new career high singles ranking of World No. 2 following the event. Later that year, Ivanovic reached her third grand slam singles final by defeating Jelena Jankovic in three sets in the semi-finals and thus ensured that she would become the World No. 1 for the first time in her career. Ivanovic then defeated first time grand slam singles finalist, Dinara Safina in the final in straight sets to win her first (and thus far) only grand slam singles title.
At the 2012 US Open, Ivanovic defeated Tsvetana Pironkova in the fourth round, dropping just four games to reach her first US Open quarterfinal and her first grand slam singles quarterfinal since 2008. With this achievement, Ivanovic has now reached the quarterfinals or better at all four grand slam events.
(W) winner; (F) finalist; (SF) semifinalist; (QF) quarterfinalist; (#R) rounds 4, 3, 2, 1; (RR) round-robin stage; (Q#) qualification round; (P#) preliminary round; (DNQ) did not qualify; (A) absent; (Z#) Davis/Fed Cup Zonal Group (with number indication) or (PO) play-off; (G) gold, (S) silver or (B) bronze Olympic/Paralympic medal; (NMS) not a Masters tournament; (NTI) not a Tier I tournament; (P) postponed; (NH) not held; (SR) strike rate (events won / competed); (W–L) win–loss record.
To avoid confusion and double counting, these charts are updated at the conclusion of a tournament or when the player's participation has ended.