She moved to Manchester in 1990 and to begin work at the Stockport Express Advertiser. She moved into local radio, working for Signal Radio in Stoke and BRMB in Birmingham, before becoming a presenter and reporter for the local cable television station Birmingham Live TV, which Tiffin launched in 1995 as the first person on air. After 18 months, she moved to Central Television in Nottingham and became a reporter and bulletin presenter for Central News East.
Tiffin joined BBC North West in 2003 as a presenter and producer for the late North West Tonight bulletin on weekdays. She later became a regular stand-in anchor on the main evening programme before becoming a main anchor in May 2012. Alongside regional news, she has also worked on regional current affairs series Inside Out North West and The Politics Show as well as coverage of local and general elections.