Avermitilol synthase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Avermitilol synthase
Identifiers
EC number 4.2.3.96
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Avermitilol synthase (EC 4.2.3.96) is an enzyme with systematic name avermitilol hydrolase (cyclizing, avermitilol-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O avermitilol + diphosphate

This enzyme requires Mg2+.

References[edit]

  1. ^ Chou, W.K.; Fanizza, I.; Uchiyama, T.; Komatsu, M.; Ikeda, H.; Cane, D.E. (2010). "Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol". J. Am. Chem. Soc. 132: 8850–8851. doi:10.1021/ja103087w. PMC 2904616Freely accessible. PMID 20536237. 

External links[edit]