BAG2

BAG2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3CQX, 3D0T
Identifiers
Aliases	BAG2, BAG-2, dJ417I1.2, BCL2 associated athanogene 2, BAG cochaperone 2
External IDs	OMIM: 603882; MGI: 1891254; HomoloGene: 31233; GeneCards: BAG2; OMA:BAG2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	57,189,833 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	33,796,876 bp
RNA expression pattern
	Top expressed in
	tail of epididymis; ; right ventricle; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; saphenous vein; ; seminal vesicula; ; smooth muscle tissue; ; thoracic diaphragm; ; muscle layer of sigmoid colon; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	interventricular septum; ; cardiac muscle tissue of left ventricle; ; yolk sac; ; right ventricle; ; extraocular muscle; ; entorhinal cortex; ; perirhinal cortex; ; temporal muscle; ; digastric muscle; ; lumbar spinal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	chaperone binding; protein binding; identical protein binding; adenyl-nucleotide exchange factor activity; heat shock protein binding; ubiquitin protein ligase binding; transmembrane transporter binding; tau protein binding;
Cellular component	cytosol; microtubule; axon; dendrite; chaperone complex; dendritic microtubule;
Biological process	regulation of cellular response to heat; protein metabolic process; protein folding; regulation of catalytic activity; positive regulation of protein processing; negative regulation of protein ubiquitination; negative regulation of protein binding; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein stabilization; positive regulation of proteasomal protein catabolic process; negative regulation of ubiquitin protein ligase activity;
	Sources:Amigo / QuickGO
Orthologs
	9532
	213539
	ENSG00000112208
	ENSMUSG00000042215
	O95816
	Q91YN9
	NM_004282
	NM_145392
	NP_004273
	NP_663367
	Wikidata
View/Edit Human	View/Edit Mouse

BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene.^[5]^[6]

Template:PBB Summary

Interactions

BAG2 has been shown to interact with HSPA8.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112208 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042215 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Takayama S, Xie Z, Reed JC (Feb 1999). "An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators". J Biol Chem. 274 (2): 781–6. doi:10.1074/jbc.274.2.781. PMID 9873016.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: BAG2 BCL2-associated athanogene 2".

External links

Human BAG2 genome location and BAG2 gene details page in the UCSC Genome Browser.

Interactions

References

External links

Further reading