BCL2L14

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BCL2L14
Identifiers
Aliases BCL2L14, BCLG, BCL2 like 14
External IDs MGI: 1914063 HomoloGene: 49840 GeneCards: BCL2L14
RNA expression pattern
PBB GE BCL2L14 221241 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030766
NM_138722
NM_138723
NM_138724

NM_025778

RefSeq (protein)

NP_110393
NP_620048
NP_620049

NP_080054.1
NP_080054

Location (UCSC) Chr 12: 12.05 – 12.21 Mb Chr 6: 134.4 – 134.44 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Apoptosis facilitator Bcl-2-like protein 14 is a protein that in humans is encoded by the BCL2L14 gene.[3][4]

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Four alternatively spliced transcript variants, which encode three distinct isoforms, have been reported for this gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Guo B, Godzik A, Reed JC (May 2001). "Bcl-G, a novel pro-apoptotic member of the Bcl-2 family". J Biol Chem. 276 (4): 2780–5. doi:10.1074/jbc.M005889200. PMID 11054413. 
  4. ^ a b "Entrez Gene: BCL2L14 BCL2-like 14 (apoptosis facilitator)". 

External links[edit]

Further reading[edit]