BIRC7

BIRC7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1OXN, 1OXQ, 1OY7, 1TW6, 2I3H, 2I3I, 3F7G, 3F7H, 3F7I, 3GT9, 3GTA, 3UW5, 4AUQ
Identifiers
Aliases	BIRC7, KIAP, LIVIN, ML-IAP, MLIAP, RNF50, baculoviral IAP repeat containing 7
External IDs	OMIM: 605737; MGI: 2676458; HomoloGene: 51405; GeneCards: BIRC7; OMA:BIRC7 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	63,240,495 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	180,575,803 bp
RNA expression pattern
	Top expressed in
	tibial nerve; ; sural nerve; ; placenta; ; right adrenal cortex; ; right lung; ; gonad; ; skin of leg; ; skin of abdomen; ; lymph node; ; C1 segment;
	Top expressed in
	lens; ; epithelium of lens; ; set of lens fibers; ; ankle; ; embryo; ; dentate gyrus; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; primary visual cortex; ; neural tube;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase inhibitor activity; cysteine-type endopeptidase inhibitor activity; metal ion binding; ubiquitin-protein transferase activity; protein binding; enzyme binding; transferase activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; ubiquitin protein ligase activity;
Cellular component	cytoplasm; Golgi apparatus; nucleus; microtubule organizing center; cytosol;
Biological process	negative regulation of peptidase activity; inhibition of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of apoptotic process; regulation of natural killer cell apoptotic process; mitotic spindle assembly; regulation of cell population proliferation; regulation of signal transduction; protein ubiquitination; apoptotic process; positive regulation of protein ubiquitination; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	79444
	329581
	ENSG00000101197
	ENSMUSG00000038840
	Q96CA5
	A2AWP0
	NM_139317; NM_022161
	NM_001163247
	NP_071444; NP_647478
	NP_001156719
	Wikidata
View/Edit Human	View/Edit Mouse

Baculoviral IAP repeat-containing protein 7 is a protein that in humans is encoded by the BIRC7 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000101197 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038840 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kasof GM, Gomes BC (May 2001). "Livin, a novel inhibitor of apoptosis protein family member". J Biol Chem. 276 (5): 3238–46. doi:10.1074/jbc.M003670200. PMID 11024045.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Lin JH, Deng G, Huang Q, Morser J (Feb 2001). "KIAP, a novel member of the inhibitor of apoptosis protein family". Biochem Biophys Res Commun. 279 (3): 820–31. doi:10.1006/bbrc.2000.4027. PMID 11162435.
^ "Entrez Gene: BIRC7 baculoviral IAP repeat-containing 7 (livin)".

External links

Human BIRC7 genome location and BIRC7 gene details page in the UCSC Genome Browser.

References

External links

Further reading