BNR/Asp-box repeat
| BNR/Asp-box repeat | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Structure of a bacterial sialidase.[1] | |||||||||
| Identifiers | |||||||||
| Symbol | BNR | ||||||||
| Pfam | PF02012 | ||||||||
| Pfam clan | CL0434 | ||||||||
| InterPro | IPR002860 | ||||||||
| SCOP2 | 1euu / SCOPe / SUPFAM | ||||||||
| |||||||||
BNR/Asp-box repeat is a repetitive sequence of amino acids contained in some proteins.
Members of this family contain multiple BNR (bacterial neuraminidase repeat) repeats or Asp-boxes. The repeats are short, however the repeats are never found closer than 40 residues together suggesting that the repeat is structurally longer. These repeats are found in a variety of non-homologous proteins, including bacterial ribonucleases, sulphite oxidases, reelin, netrins, sialidases, neuraminidases, some lipoprotein receptors, and a variety of glycosyl hydrolases.[2]
Members of this family contain multiple BNR (bacterial neuraminidase repeat) repeats or Asp-boxes.
Examples
Human genes encoding proteins containing this domain include:
References
- ^ Gaskell A, Crennell S, Taylor G (November 1995). "The three domains of a bacterial sialidase: a beta-propeller, an immunoglobulin module and a galactose-binding jelly-roll". Structure. 3 (11): 1197–205. doi:10.1016/s0969-2126(01)00255-6. PMID 8591030.
- ^ Copley RR, Russell RB, Ponting CP (February 2001). "Sialidase-like Asp-boxes: sequence-similar structures within different protein folds". Protein Science. 10 (2): 285–92. doi:10.1110/ps.31901. PMC 2373934. PMID 11266614.