In statistics, the use of Bayes factors is a Bayesian alternative to classical hypothesis testing. Bayesian model comparison is a method of model selection based on Bayes factors. The models under consideration are statistical models. The aim of the Bayes factor is to quantify the support for a model over another, regardless of whether these models are correct. The technical definition of "support" in the context of Bayesian inference is described below.
The key data-dependent term represents the probability that some data are produced under the assumption of the model M; evaluating it correctly is the key to Bayesian model comparison.
Given a model selection problem in which we have to choose between two models on the basis of observed data D, the plausibility of the two different models M1 and M2, parametrised by model parameter vectors and , is assessed by the Bayes factor K given by
When the two models are equally probable a priori, so that , the Bayes factor is equal to the ratio of the posterior probabilities of M1 and M2. If instead of the Bayes factor integral, the likelihood corresponding to the maximum likelihood estimate of the parameter for each statistical model is used, then the test becomes a classical likelihood-ratio test. Unlike a likelihood-ratio test, this Bayesian model comparison does not depend on any single set of parameters, as it integrates over all parameters in each model (with respect to the respective priors). However, an advantage of the use of Bayes factors is that it automatically, and quite naturally, includes a penalty for including too much model structure. It thus guards against overfitting. For models where an explicit version of the likelihood is not available or too costly to evaluate numerically, approximate Bayesian computation can be used for model selection in a Bayesian framework, with the caveat that approximate-Bayesian estimates of Bayes factors are often biased.
Other approaches are:
- to treat model comparison as a decision problem, computing the expected value or cost of each model choice;
- to use minimum message length (MML).
A value of K > 1 means that M1 is more strongly supported by the data under consideration than M2. Note that classical hypothesis testing gives one hypothesis (or model) preferred status (the 'null hypothesis'), and only considers evidence against it. Harold Jeffreys gave a scale for interpretation of K:
|K||dHart||bits||Strength of evidence|
|< 100||0||—||Negative (supports M2)|
|100 to 101/2||0 to 5||0 to 1.6||Barely worth mentioning|
|101/2 to 101||5 to 10||1.6 to 3.3||Substantial|
|101 to 103/2||10 to 15||3.3 to 5.0||Strong|
|103/2 to 102||15 to 20||5.0 to 6.6||Very strong|
|> 102||> 20||> 6.6||Decisive|
The second column gives the corresponding weights of evidence in decihartleys (also known as decibans); bits are added in the third column for clarity. According to I. J. Good a change in a weight of evidence of 1 deciban or 1/3 of a bit (i.e. a change in an odds ratio from evens to about 5:4) is about as finely as humans can reasonably perceive their degree of belief in a hypothesis in everyday use.
An alternative table, widely cited, is provided by Kass and Raftery (1995):
|2 ln K||K||Strength of evidence|
|0 to 2||1 to 3||Not worth more than a bare mention|
|2 to 6||3 to 20||Positive|
|6 to 10||20 to 150||Strong|
|> 10||> 150||Very strong|
The use of Bayes factors or classical hypothesis testing takes place in the context of inference rather than decision-making under uncertainty. That is, we merely wish to find out which hypothesis is true, rather than actually making a decision on the basis of this information. Frequentist statistics draws a strong distinction between these two because classical hypothesis tests are not coherent in the Bayesian sense. Bayesian procedures, including Bayes factors, are coherent, so there is no need to draw such a distinction. Inference is then simply regarded as a special case of decision-making under uncertainty in which the resulting action is to report a value. For decision-making, Bayesian statisticians might use a Bayes factor combined with a prior distribution and a loss function associated with making the wrong choice. In an inference context the loss function would take the form of a scoring rule. Use of a logarithmic score function for example, leads to the expected utility taking the form of the Kullback–Leibler divergence.
Suppose we have a random variable that produces either a success or a failure. We want to compare a model M1 where the probability of success is q = ½, and another model M2 where q is unknown and we take a prior distribution for q that is uniform on [0,1]. We take a sample of 200, and find 115 successes and 85 failures. The likelihood can be calculated according to the binomial distribution:
Thus we have
The ratio is then 1.197..., which is "barely worth mentioning" even if it points very slightly towards M1.
A frequentist hypothesis test of M1 (here considered as a null hypothesis) would have produced a very different result. Such a test says that M1 should be rejected at the 5% significance level, since the probability of getting 115 or more successes from a sample of 200 if q = ½ is 0.0200, and as a two-tailed test of getting a figure as extreme as or more extreme than 115 is 0.0400. Note that 115 is more than two standard deviations away from 100. Thus, whereas a frequentist hypothesis test would yield significant results at the 5% significance level, the Bayes factor hardly considers this to be an extreme result. Note, however, that a non-uniform prior (for example one that reflects the fact that you expect the number of success and failures to be of the same order of magnitude) could result in a Bayes factor that is more in agreement with the frequentist hypothesis test.
(rather than averaging over all possible q). That gives a likelihood ratio of 0.1045 and points towards M2.
M2 is a more complex model than M1 because it has a free parameter which allows it to model the data more closely. The ability of Bayes factors to take this into account is a reason why Bayesian inference has been put forward as a theoretical justification for and generalisation of Occam's razor, reducing Type I errors.
On the other hand, the modern method of relative likelihood takes into account the number of free parameters in the models, unlike the classical likelihood ratio. The relative likelihood method could be applied as follows. Model M1 has 0 parameters, and so its AIC value is 2·0 − 2·ln(0.005956) = 10.2467. Model M2 has 1 parameter, and so its AIC value is 2·1 − 2·ln(0.056991) = 7.7297. Hence M1 is about exp((7.7297 − 10.2467)/2) = 0.284 times as probable as M2 to minimize the information loss. Thus M2 is slightly preferred, but M1 cannot be excluded.
- Bayes factor has been applied to rank dynamic differential expression genes instead of q-value.
- Akaike information criterion
- Approximate Bayesian computation
- Bayesian information criterion
- Deviance information criterion
- Lindley's paradox
- Minimum message length
- Model selection
- Statistical ratios
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