Bridging integrator 3

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BIN3
Identifiers
Aliases BIN3, bridging integrator 3
External IDs MGI: 1929883 HomoloGene: 5472 GeneCards: BIN3
Gene location (Human)
Chromosome 8 (human)
Chr. Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for BIN3
Genomic location for BIN3
Band 8p21.3 Start 22,620,418 bp[1]
End 22,669,148 bp[1]
RNA expression pattern
PBB GE BIN3 222199 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018688

NM_021328

RefSeq (protein)

NP_061158

NP_067303

Location (UCSC) Chr 8: 22.62 – 22.67 Mb Chr 8: 70.1 – 70.14 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Bridging integrator 3 is a protein that in humans is encoded by the BIN3 gene.[5][6]

Function[edit]

The product of this gene is a member of the BAR domain protein family. The encoded protein is composed solely of a BAR domain which is predicted to form coiled coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.[6]

References[edit]

External links[edit]

Further reading[edit]