FRA10AC1

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FRA10AC1
Identifiers
Aliases FRA10AC1, C10orf4, F26C11.1-like, FRA10A, fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1, FRA10A associated CGG repeat 1
External IDs MGI: 1917817 HomoloGene: 13852 GeneCards: FRA10AC1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001081075

RefSeq (protein)

NP_001334641
NP_001334642
NP_001334643
NP_001334644
NP_660289

NP_001074544.1
NP_001074544

Location (UCSC) Chr 10: 93.67 – 93.7 Mb Chr 19: 38.19 – 38.22 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

FRA10AC1 is a protein that in humans is encoded by the FRA10AC1 gene.[3]

Function[edit]

The protein encoded by this gene is a nuclear phosphoprotein of unknown function. The 5' UTR of this gene is part of a CpG island and contains a tandem CGG repeat region that normally consists of 8-14 repeats but can expand to over 200 repeats. The expanded allele becomes hyper-methylated and is not transcribed; however, an expanded repeat region has not been associated with any disease phenotype. This gene is found within the rare FRA10A folate-sensitive fragile site.[3]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.