Elongator complex protein 5

ELP5
Identifiers
Aliases	ELP5, C17orf81, DERP6, MST071, MSTP071, HSPC002, elongator acetyltransferase complex subunit 5
External IDs	OMIM: 615019; MGI: 1859017; HomoloGene: 10291; GeneCards: ELP5; OMA:ELP5 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	7,259,940 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	69,873,343 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; apex of heart; ; mucosa of transverse colon; ; left ventricle; ; smooth muscle tissue; ; right adrenal gland; ; right adrenal cortex; ; muscle of thigh; ; ventricular zone;
	Top expressed in
	spermatocyte; ; spermatid; ; medial ganglionic eminence; ; yolk sac; ; embryo; ; morula; ; ventricular zone; ; embryo; ; seminiferous tubule; ; endocardial cushion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	nucleus; cytoplasm; elongator holoenzyme complex; cytosol;
Biological process	regulation of transcription, DNA-templated; positive regulation of cell migration; transcription, DNA-templated; tRNA wobble uridine modification;
	Sources:Amigo / QuickGO
Orthologs
	23587
	54351
	ENSG00000170291; ENSG00000288485
	ENSMUSG00000018565
	Q8TE02
	Q99L85
	NM_015362; NM_203413; NM_203414; NM_203415
	NM_001253700; NM_018740
	NP_056177; NP_981958; NP_981959; NP_981960
	NP_001240629; NP_061210
	Wikidata
View/Edit Human	View/Edit Mouse

Elongator complex protein 5 (ELP5) also known as dermal papilla-derived protein 6 (DERP6) is a protein that in humans is encoded by the ELP5 gene.^[5]^[6]

References

^ ^a ^b ^c ENSG00000288485 GRCh38: Ensembl release 89: ENSG00000170291, ENSG00000288485 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018565 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
^ "Entrez Gene: C17orf81 chromosome 17 open reading frame 81".

Yuan J, Tang W, Luo K, et al. (2006). "Cloning and characterization of the human gene DERP6, which activates transcriptional activities of p53". Mol. Biol. Rep. 33 (3): 151–8. doi:10.1007/s11033-006-6273-5. PMID 16850183. S2CID 21300065.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] ENSG00000288485 GRCh38: Ensembl release 89: ENSG00000170291, ENSG00000288485 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018565 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11042152-5] Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.

[entrez-6] "Entrez Gene: C17orf81 chromosome 17 open reading frame 81".

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References

Further reading