CHFR

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CHFR
Protein CHFR PDB 1lgp.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CHFR, RNF116, RNF196, checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
External IDs MGI: 2444898 HomoloGene: 10078 GeneCards: CHFR
RNA expression pattern
PBB GE CHFR 218803 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018223
NM_001161344
NM_001161345
NM_001161346
NM_001161347

NM_001289577
NM_001289578
NM_001289579
NM_001289580
NM_172717

RefSeq (protein)

NP_001154816
NP_001154817
NP_001154818
NP_001154819
NP_060693

Location (UCSC) Chr 12: 132.82 – 132.96 Mb Chr 5: 110.14 – 110.17 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

E3 ubiquitin-protein ligase CHFR is an enzyme that in humans is encoded by the CHFR gene.[3][4][5]


References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Scolnick DM, Halazonetis TD (Aug 2000). "Chfr defines a mitotic stress checkpoint that delays entry into metaphase". Nature. 406 (6794): 430–5. doi:10.1038/35019108. PMID 10935642. 
  4. ^ Kang D, Chen J, Wong J, Fang G (Jan 2002). "The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition". J Cell Biol. 156 (2): 249–59. doi:10.1083/jcb.200108016. PMC 2199220Freely accessible. PMID 11807090. 
  5. ^ "Entrez Gene: CHFR checkpoint with forkhead and ring finger domains". 

External links[edit]

Further reading[edit]