CLDN10

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CLDN10
Identifiers
Aliases CLDN10, CPETRL3, OSP-L, claudin 10
External IDs MGI: 1913101 HomoloGene: 5076 GeneCards: CLDN10
RNA expression pattern
PBB GE CLDN10 205328 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001160100
NM_006984
NM_182848

RefSeq (protein)

NP_001153572
NP_008915
NP_878268

Location (UCSC) Chr 13: 95.43 – 95.58 Mb Chr 14: 118.79 – 118.88 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Claudin-10 is a protein that in humans is encoded by the CLDN10 gene.[3][4] It belongs to the group of claudins.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Two alternatively spliced transcript variants that encode different isoforms have been identified for this gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ip YC, Cheung ST, Lee YT, Ho JC, Fan ST (Nov 2007). "Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells". Mol Cancer Ther. 6 (11): 2858–67. doi:10.1158/1535-7163.MCT-07-0453. PMID 18025272. 
  4. ^ a b "Entrez Gene: CLDN10 claudin 10". 

External links[edit]

Further reading[edit]