CLDN4

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CLDN4
Identifiers
AliasesCLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R, claudin 4
External IDsMGI: 1313314 HomoloGene: 1000 GeneCards: CLDN4
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for CLDN4
Genomic location for CLDN4
Band7q11.23Start73,799,542 bp[1]
End73,832,693 bp[1]
RNA expression pattern
PBB GE CLDN4 201428 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001305

NM_009903

RefSeq (protein)

NP_001296

NP_034033

Location (UCSC)Chr 7: 73.8 – 73.83 MbChr 5: 134.95 – 134.95 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins.

This gene encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000189143 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047501 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: CLDN4 claudin 4".

External links[edit]

Further reading[edit]