CLDN6

CLDN6
Identifiers
Aliases	CLDN6, claudin 6
External IDs	OMIM: 615798; MGI: 1859284; HomoloGene: 10300; GeneCards: CLDN6; OMA:CLDN6 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) Band 16p13.3 Start 3,014,712 bp End 3,020,071 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17|17 A3.3 Start 23,898,223 bp End 23,901,420 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans putamen placenta cerebellar hemisphere striated muscle tissue skeletal muscle tissue stromal cell of endometrium metanephros caudate nucleus body of pancreas Top expressed in yolk sac primitive streak blastocyst glomerulus morula renal vein saccule maxillary prominence otic placode urethra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity identical protein binding protein binding virus receptor activity Cellular component bicellular tight junction cell junction membrane apicolateral plasma membrane integral component of membrane plasma membrane Biological process cell-cell junction organization viral process calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules viral entry into host cell Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9074 54419 Ensembl ENSG00000184697 ENSMUSG00000023906 UniProt P56747 Q9Z262 RefSeq (mRNA) NM_021195 NM_018777 RefSeq (protein) NP_067018 NP_061247 Location (UCSC) Chr 16: 3.01 – 3.02 Mb Chr 17: 23.9 – 23.9 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Claudin-6 is a protein that in humans is encoded by the CLDN6 gene. It belongs to the group of claudins.

Further reading

• Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS (2015). "A systems proteomics view of the endogenous human claudin protein family". J Proteome Res. doi:10.1021/acs.jproteome.5b00769. PMID 26680015.