CLEC1A

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CLEC1A
Identifiers
Aliases CLEC1A, CLEC-1, CLEC1, C-type lectin domain family 1 member A
External IDs MGI: 2444151 HomoloGene: 9549 GeneCards: CLEC1A
RNA expression pattern
PBB GE CLEC1A 219761 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001297748
NM_001297749
NM_001297750
NM_001297751
NM_016511

NM_175526
NM_001347475

RefSeq (protein)

NP_780735.2
NP_001334404
NP_780735

Location (UCSC) Chr 12: 10.07 – 10.11 Mb Chr 6: 129.42 – 129.45 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

C-type lectin domain family 1 member A is a protein that in humans is encoded by the CLEC1A gene.[3][4][5]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded protein may play a role in regulating dendritic cell function. Alternative splice variants have been described but their biological nature has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Colonna M, Samaridis J, Angman L (Mar 2000). "Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells". Eur J Immunol. 30 (2): 697–704. doi:10.1002/1521-4141(200002)30:2<697::AID-IMMU697>3.0.CO;2-M. PMID 10671229. 
  4. ^ Sobanov Y, Bernreiter A, Derdak S, Mechtcheriakova D, Schweighofer B, Duchler M, Kalthoff F, Hofer E (Dec 2001). "A novel cluster of lectin-like receptor genes expressed in monocytic, dendritic and endothelial cells maps close to the NK receptor genes in the human NK gene complex". Eur J Immunol. 31 (12): 3493–503. doi:10.1002/1521-4141(200112)31:12<3493::AID-IMMU3493>3.0.CO;2-9. PMID 11745369. 
  5. ^ a b "Entrez Gene: CLEC1A C-type lectin domain family 1, member A". 

Further reading[edit]