CSN2

CSN2
Identifiers
Aliases	CSN2, CASB, casein beta, PDC213
External IDs	OMIM: 115460; MGI: 88541; HomoloGene: 1426; GeneCards: CSN2; OMA:CSN2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	69,965,728 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	87,847,489 bp
RNA expression pattern
	Top expressed in
	testicle; ; tonsil; ; salivary gland; ; minor salivary glands; ; olfactory zone of nasal mucosa; ; islet of Langerhans; ; smooth muscle tissue; ; placenta; ; urinary bladder; ; skeletal muscle;
	Top expressed in
	lactiferous gland; ; parotid gland; ; muscle of thigh; ; thymus; ; mesenteric lymph nodes; ; umbilical cord; ; tibiofemoral joint; ; dorsal striatum; ; choroid plexus of fourth ventricle; ; sexually immature organism;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; enzyme inhibitor activity; transporter activity; cysteine-type endopeptidase inhibitor activity;
Cellular component	extracellular region; extracellular space;
Biological process	negative regulation of lactation; lactation; calcium ion transport; negative regulation of cysteine-type endopeptidase activity; transport;
	Sources:Amigo / QuickGO
Orthologs
	1447
	12991
	ENSG00000135222; ENSG00000283030
	ENSMUSG00000063157
	P05814
	P10598
	NM_001302770; NM_001891; NM_001385731
NM_001286020; NM_001286021; NM_001286022; NM_001286023; NM_001286024;
	NM_009972
	NP_001289699; NP_001882
NP_001272949; NP_001272950; NP_001272951; NP_001272952; NP_001272953;
	NP_034102
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-casein is a protein that in humans is encoded by the CSN2 gene.^[5]^[6] It is in the class of phosphoproteins and generally occurs in mammalian milk.

Template:PBB Summary

References

^ ^a ^b ^c ENSG00000283030 GRCh38: Ensembl release 89: ENSG00000135222, ENSG00000283030 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000063157 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Menon RS, Chang YF, Jeffers KF, Jones C, Ham RG (Jun 1992). "Regional localization of human beta-casein gene (CSN2) to 4pter-q21". Genomics. 13 (1): 225–6. doi:10.1016/0888-7543(92)90227-J. PMID 1577486.
^ "Entrez Gene: CSN2 casein beta".

References

Further reading