CWC15

CWC15
Identifiers
Aliases	CWC15, AD002, C11orf5, Cwf15, HSPC148, ORF5, CWC15 spliceosome-associated protein, CWC15 spliceosome associated protein homolog
External IDs	MGI: 1913320; HomoloGene: 9499; GeneCards: CWC15; OMA:CWC15 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	94,973,586 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	14,421,873 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; cardiac muscle tissue of right atrium; ; myocardium of left ventricle; ; Skeletal muscle tissue of rectus abdominis; ; vastus lateralis muscle; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; body of tongue; ; muscle of thigh; ; left testis;
	Top expressed in
	ventricular zone; ; neural layer of retina; ; muscle of thigh; ; morula; ; yolk sac; ; embryo; ; epiblast; ; embryo; ; tail of embryo; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	catalytic step 2 spliceosome; spliceosomal complex; nucleus; nucleoplasm; mitochondrion; nuclear speck; U2-type catalytic step 2 spliceosome;
Biological process	mRNA processing; RNA splicing; mRNA splicing, via spliceosome; mRNA cis splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	51503
	66070
	ENSG00000150316
	ENSMUSG00000004096
	Q9P013
	Q9JHS9
	NM_016403; NM_001363371; NM_001363372
	NM_023153
	NP_057487; NP_001350300; NP_001350301
	NP_075642
	Wikidata
View/Edit Human	View/Edit Mouse

Protein CWC15 homolog is a protein that in humans is encoded by the CWC15 gene.^[5]^[6]^[7]

Interactions

CWC15 has been shown to interact with CDC5L.^[8]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000150316 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000004096 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ O'Brien KP, Tapia-Paez I, Stahle-Backdahl M, Kedra D, Dumanski JP (Jul 2000). "Characterization of five novel human genes in the 11q13-q22 region". Biochem Biophys Res Commun. 273 (1): 90–4. doi:10.1006/bbrc.2000.2910. PMID 10873569.
^ Ohi MD, Link AJ, Ren L, Jennings JL, McDonald WH, Gould KL (Mar 2002). "Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs". Mol Cell Biol. 22 (7): 2011–24. doi:10.1128/MCB.22.7.2011-2024.2002. PMC 133674. PMID 11884590.
^ "Entrez Gene: HSPC148 hypothetical protein HSPC148".
^ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (Dec 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. 19 (23). ENGLAND: 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)