Cytokine-like 1 is a protein that in humans is encoded by the CYTL1 gene.
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Function
C17 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 (MIM 142230) surface marker[PubMed 10857752]). Functionally, C17 was identified as a secretory protein expressed in CD34+ haemopoietic cells [PMID 10857752]. CYTL1 seems to regulate chondrogenesis and is required for the maintenance of cartilage homeostasis and might, additionally, work as a regulatory factor in embryo implantation in the stage of early pregnancy.[6]
This family of proteins, C17, is found in vertebrates. Proteins have two conserved sequence motifs: PPTCYSR and DDC.
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