Calcium-regulated heat stable protein 1

CARHSP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3AQQ
Identifiers
Aliases	CARHSP1, CRHSP-24, CSDC1, CRHSP24, calcium regulated heat stable protein 1
External IDs	OMIM: 616885; MGI: 1196368; HomoloGene: 8632; GeneCards: CARHSP1; OMA:CARHSP1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	8,869,012 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	8,490,019 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; ganglionic eminence; ; ventricular zone; ; right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; right lobe of liver; ; right lung;
	Top expressed in
	lens; ; granulocyte; ; cumulus cell; ; epithelium of lens; ; fetal liver hematopoietic progenitor cell; ; secondary oocyte; ; medial ganglionic eminence; ; tibiofemoral joint; ; blood; ; renal corpuscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	mRNA 3'-UTR binding; DNA binding; phosphatase binding; protein binding; RNA binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasmic exosome (RNase complex); cytosol; P-body; P granule; cytoplasm;
Biological process	intracellular signal transduction; regulation of transcription, DNA-templated; regulation of mRNA stability; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	23589
	52502
	ENSG00000153048
	ENSMUSG00000008393
	Q9Y2V2
	Q9CR86
NM_001042476; NM_001278260; NM_001278261; NM_001278262; NM_001278263;
	NM_001278264; NM_001278265; NM_001278266; NM_014316
	NM_025821
NP_001035941; NP_001265189; NP_001265190; NP_001265191; NP_001265192;
	NP_001265193; NP_001265194; NP_001265195; NP_055131
	NP_080097
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium-regulated heat stable protein 1 (CARHSP1) also known as calcium-regulated heat-stable protein of 24 kDa (CRHSP-24) is a protein that in humans is encoded by the CARHSP1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000153048 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000008393 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Groblewski GE, Yoshida M, Bragado MJ, Ernst SA, Leykam J, Williams JA (Sep 1998). "Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells". J Biol Chem. 273 (35): 22738–44. doi:10.1074/jbc.273.35.22738. PMID 9712905.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: CARHSP1 calcium regulated heat stable protein 1, 24kDa".

Wishart MJ, Dixon JE (2002). "The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production". Proc. Natl. Acad. Sci. U.S.A. 99 (4): 2112–7. doi:10.1073/pnas.251686198. PMC 122327. PMID 11842224.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Schäfer C, Steffen H, Krzykowski KJ, et al. (2003). "CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells". Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4): G726–34. doi:10.1152/ajpgi.00111.2003. PMID 12801884.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". J. Proteome Res. 4 (4): 1339–46. doi:10.1021/pr050048h. PMID 16083285.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000153048 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000008393 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9712905-5] Groblewski GE, Yoshida M, Bragado MJ, Ernst SA, Leykam J, Williams JA (Sep 1998). "Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells". J Biol Chem. 273 (35): 22738–44. doi:10.1074/jbc.273.35.22738. PMID 9712905.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[entrez-6] "Entrez Gene: CARHSP1 calcium regulated heat stable protein 1, 24kDa".

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References

Further reading