|Districts||Southern Belmont County, Northern Monroe County|
|Source||North Fork Captina Creek|
|- location||Near Barnesville, Ohio, Belmont County, Midwest, Ohio|
|- location||Powhatan Point, Ohio, Belmont County, Midwest, Ohio|
|Length||35 mi (56 km)|
|Basin||227 sq mi (588 km2)|
Captina Creek is a semi-large creek, which feeds directly into the Ohio River, located in southeastern Ohio. Captina Creek is an important creek to the region and home to about 56 species of fish. Captina Creek is dotted with many small attractions such as the Horseshoe Bend Golf Course, Brubaker's Groccery Store, Clair Mar Golf Course, Pebble Beach, and many others.
In April, 1774, the frontiersman Michael Cresap was accused of killing two Indians at the mouth of Captina Creek in revenge for the murder of a white trader earlier that month. He was later exonerated. This, and the subsequent Yellow Creek Massacre (April 30, 1774), were the sole causes of Lord Dunmore's War (1774). There is a plaque, which is located inside a gazebo on the Powhatan Point village fair grounds, dedicated to George Washington at the mouth of the creek. The plaque states that Washington had set camp for a night at the mouth of Captina creek while exploring the Ohio Valley.
Captina Creek is located in the southeastern part of Ohio. The creek is parallel by State Route 148, which runs from the mouth at the Ohio river, past the source near Barnesville . Chestnut Creek and Barnesville Reservoir Number Two, along with other small streams and rainwater, are the main sources for the creek which flows southeast towards the Ohio River. For more information on townships located along State Route 148, see article State Route 148 (SR 148).
- Albach, James R (1858), Annals of the West: embracing a concise account of principal events which have occurred in the Western States and Territories from the discovery of the Mississippi Valley to the Year Eighteen Hundred and Fifty-Seven compiled from the most authentic sources and published by James R. Albach; Pittsburgh: W.S. Haven, Book and Job Printer, pp 217-219.
- "2009 Water Quality Monitoring Central Ohio River Tributaries and Watersheds". Ohio Environmental Protection Agency. Archived from the original on 27 December 2010. Retrieved 26 March 2011.