|Christopher A. Voigt|
|Born||Ann Arbor, Michigan|
|Institutions||UCSF, Massachusetts Institute of Technology|
|Alma mater||University of Michigan, California Institute of Technology, University of California - Berkeley|
|Doctoral advisor||Zhen-Gang Wang, Frances Arnold, Stephen Mayo, Adam P Arkin|
Christopher Voigt is an American synthetic biologist, molecular biophysicist, and engineer. He is an Associate Professor in the Department of Biological Engineering] at the Massachusetts Institute of Technology (MIT). His research interests focus on the reprogramming of bacterial organisms to perform coordinated, complex tasks for pharmaceutical and industrial applications. He is a member of the National Science Foundation-funded Synthetic Biology Engineering Research Center, called SynBERC, and works in the developing field of synthetic biology. His recent works include:
- Engineering a bacterial two-component system to regulate gene expression in response to red light.
- Engineering bacteria to sense its environment and conditionally invade cancer cells either when the concentration of bacteria is large enough, when the environment has little oxygen (e.g., inside a tumor), or when a specific chemical is present.
- Constructing a logical AND gate inside bacteria.
Current research projects use these new environmental sensors and logical switches to control the assembly and function of newly redesigned systems, such as a secretion needle that exports spider silk proteins or a photosynthetic apparatus responsible for converting light into chemical energy.
- Levskaya A, Chevalier AA, Tabor JJ, Simpson ZB, Lavery LA, Levy M, Davidson EA, Scouras A, Ellington AD, Marcotte EM, Voigt CA (2005). "Synthetic biology: engineering Escherichia coli to see light". Nature. 438 (7067): 441–2. doi:10.1038/nature04405. PMID 16306980.
- Anderson JC, Clarke EJ, Arkin AP, Voigt CA (2006). "Environmentally controlled invasion of cancer cells by engineered bacteria". J. Mol. Biol. 355 (4): 619–27. doi:10.1016/j.jmb.2005.10.076. PMID 16330045.
- Anderson JC, Voigt CA, Arkin AP (2007). "Environmental signal integration by a modular AND gate". Mol. Syst. Biol. 3 (1): 133. doi:10.1038/msb4100173. PMC . PMID 17700541.
- "2006 Young Innovators Under 35". Technology Review. 2006. Retrieved August 15, 2011.