Defensores de Cambaceres
|Full name||Club Defensores de Cambaceres|
|Founded||12 October 1921|
|Ground||Estadio Defensores de Cambaceres
Ensenada, Buenos Aires Province, Argentina
|Manager||Alejo Santa María|
Club Defensores de Cambaceres is an Argentine football club from the city of Ensenada, Buenos Aires Province. The team currently plays in Primera C, the regionalised fourth division of the Argentine football league system.
The club was founded in 1921 with the name "Club Social y Deportivo Defensores de Cambaceres" (Defenders of Cambaceres Social and Sports Club), and the kit color (red) was chosen as an homage to Independiente, one of the most successful teams of Argentina. Cambaceres was not affiliated to the Argentine Football Association until 1957.
- Primera C (2): 1990–91, 1998–99
- Primera D (2): 1959, 1976
- Liga Amateur Platense [a] (11): 1927, 1929, 1931, 1934, 1935, 1939, 1941, 1944, 1946, 1950, 1956