|Whole body fossil of Cretolamna|
|Fossil teeth of C. biauriculata from Khouribga (Morocco)|
These sharks lived from the Aptian of the Cretaceous period to the Ypresian stage of the early Eocene epoch (115 to 48 million years ago). It is considered by many to be the ancestor of many of the famous shark genera, such as the mako, great white, Carcharocles angustidens, and Carcharocles megalodon sharks.
Cretolamna was a widespread genus in North Africa (Morocco), Near East (Jordan)  and North America on the East Coast and in the Midwest. Deposits in Morocco are usually Eocene in age, In Jordan they are of Cretaceous and Eocene in age while most deposits in the U.S. are of Cretaceous and Paleocene age. C. maroccana is more prevalent in Morocco and Jordan, while C. appendiculata is more prevalent in the United States. Both species overlapped at one point in time.
- The spelling of the name is controversial; the original spelling is Cretalamna, but currently both spellings are in use. For comments on the spelling of the genus name see: Mikael Siverson; Johan Lindgren; Michael G. Newbrey; Peter Cederström; Todd D. Cook (2015). "Cenomanian-Campanian (Late Cretaceous) mid-palaeolatitude sharks of Cretalamna appendiculata type". Acta Palaeontologica Polonica. 60 (2): 339–384. doi:10.4202/app.2012.0137.
- Welton & Farish, Bruce J. & Roger F. (1993). The Collectors's Guide to Fossil Sharks and Rays from the Cretaceous of Texas. Before Time.
- Kaddumi H. F. 2009. Fossils of the Harrana Fauna and the Adjacent Areas. Publications of the Eternal River Museum of Natural History, Amman, pp 324
- Yoost, Derek. "Potomac River Fossils". Retrieved 14 May 2012.
- Kent, Bretton W. (1987). Fossil Sharks of the Chesapeake Bay Region. Egan Rees & Boyer Inc.