DRD1IP

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CALY
Identifiers
Aliases CALY, DRD1IP, NSG3, calcyon neuron specific vesicular protein
External IDs MGI: 1915816 HomoloGene: 9256 GeneCards: CALY
Gene location (Human)
Chromosome 10 (human)
Chr. Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for CALY
Genomic location for CALY
Band 10q26.3 Start 133,324,072 bp[1]
End 133,336,935 bp[1]
RNA expression pattern
PBB GE DRD1IP 219896 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015722
NM_001321617

NM_001190385
NM_001190386
NM_026769

RefSeq (protein)

NP_001308546
NP_056537

NP_001177314
NP_001177315
NP_081045

Location (UCSC) Chr 10: 133.32 – 133.34 Mb Chr 7: 140.07 – 140.08 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Neuron-specific vesicular protein calcyon is a protein that in humans is encoded by the CALY gene.[5][6][7] Its alternative name is Calcyon.

The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with dopamine receptor D1 and may interact with other DA receptor subtypes and/or GPCRs.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130643 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025468 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Lezcano N, Mrzljak L, Eubanks S, Levenson R, Goldman-Rakic P, Bergson C (Mar 2000). "Dual signaling regulated by calcyon, a D1 dopamine receptor interacting protein". Science. 287 (5458): 1660–4. doi:10.1126/science.287.5458.1660. PMID 10698743.  (Retracted. If this is intentional, please replace {{Retracted}} with {{Retracted|intentional=yes}}.)
  6. ^ Heijtz RD, Alexeyenko A, Castellanos FX (Aug 2007). "Calcyon mRNA expression in the frontal-striatal circuitry and its relationship to vesicular processes and ADHD". Behav Brain Funct. 3 (1): 33. doi:10.1186/1744-9081-3-33. PMC 1949817Freely accessible. PMID 17623072. 
  7. ^ a b "Entrez Gene: DRD1IP dopamine receptor D1 interacting protein". 

Further reading[edit]