Daniel Geschwind

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Daniel H. Geschwind
Alma materDartmouth College, Yale School of Medicine
AwardsDerek Denny-Brown Neurological Scholar Award from the American Neurological Association (2004), member of the Institute of Medicine[1]
Scientific career
FieldsHuman genetics, neurogenetics
InstitutionsUniversity of California, Los Angeles
Doctoral advisorSusan Hockfield

Daniel H. Geschwind is the Gordon and Virginia MacDonald Distinguished Professor of Human Genetics, Neurology and Psychiatry at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). He also directs the UCLA Neurogenetics Program and the UCLA Center for Autism Research and Treatment (CART),[2] and holds the Gordon and Virginia MacDonald Distinguished Chair of Human Genetics there.[3] Since March 1, 2016, he has served as the Senior Associate Dean and Associate Vice Chancellor for Precision Medicine at UCLA.[4] His brother, Michael Geschwind, is also a professor of neurology, and behavioral neurology pioneer Norman Geschwind is his father's first cousin.[5][6][7]

Education and career[edit]

Geschwind received his A.B. degrees in psychology and chemistry at Dartmouth College, and his MD/PhD at Yale School of Medicine under the supervision of Susan Hockfield.[3] He then completed an internship at UCLA,[2] and has been a member of the UCLA faculty since 1997.[3] Geschwind has served on several scientific advisory boards and review committees, including the Faculty of 1000 Medicine, the Executive Committee of the American Neurological Association, the Scientific Advisory Board for the Allen Institute for Brain Science, the NIMH Advisory Council and the NIH Council of Councils, and served as the first chair of Cure Autism Now's scientific review committee.[7][8] Geschwind has been elected as member of the National Academy of Medicine and the Association of American Physicians.[8] As of 2016, Geschwind was the 25th highest-paid employee of the University of California system.[9]

Research[edit]

The Geschwind Lab at the UCLA David Geffin School of Medicine conducts research into three areas: autism and language, human cognitive specializations, and neurodegenerative syndromes.[3][10] He has published research examining the numerous genes involved in language, such as FOXP2, and how they differ between humans and chimpanzees.[11][12]

In 2011, Geschwind was senior author on a study which found that there are chemical differences between the brains of people with autism and the brains of people without it.[13] Specifically, Geschwind et al. found that there were common patterns in the gene expression in the frontal and temporal lobes of the brains of the autistic people they studied.[14] He is also known for his research into the factors affecting handedness in humans, and the differences in brain structure between left-handed and right-handed people.[15][16]

Awards and Prizes[edit]

References[edit]

  1. ^ "Daniel Geschwind". NAM Member Profiles.
  2. ^ a b c "Daniel H. Geschwind". UCLA Website. Retrieved 12 February 2018.
  3. ^ a b c d "Daniel Geschwind". Allen Institute for Brain Science. Archived from the original on 10 December 2014. Retrieved 5 December 2014.
  4. ^ "Daniel H. Geschwind". UCLA Newsroom. Retrieved 17 May 2016.
  5. ^ Geschwind, Michael D. (29 May 2010). "Are you Related to "the Geschwind?"". Neuropsychology Review. 20 (2): 123–125. doi:10.1007/s11065-010-9135-9. ISSN 1040-7308. PMC 2881317. PMID 20512417.
  6. ^ Wolman, David (2006). A Left Hand Turn Around the World. Da Capo Press. p. 195. ISBN 9780786734979.
  7. ^ a b Hughes, Virginia (17 February 2009). "Daniel Geschwind: After many detours, on the trail of autism's genetics". Spectrum | Autism Research News. Simons Foundation. Retrieved 8 October 2018.
  8. ^ a b "Geschwind". geschwindlab.dgsom.ucla.edu. Retrieved 8 October 2018.
  9. ^ Reese, Phillip. "All 35 of the University of California's highest-paid employees in 2016 were men". The Sacramento Bee. The McClatchy Company. Retrieved 28 January 2019.
  10. ^ "The Geschwind Lab". geschwindlab.dgsom.ucla.edu. Retrieved 8 October 2018.
  11. ^ Konopka, Genevieve; Bomar, Jamee M.; Winden, Kellen; Coppola, Giovanni; Jonsson, Zophonias O.; Gao, Fuying; Peng, Sophia; Preuss, Todd M.; Wohlschlegel, James A.; Geschwind, Daniel H. (12 November 2009). "Human-specific transcriptional regulation of CNS development genes by FOXP2". Nature. 462 (7270): 213–217. doi:10.1038/nature08549. PMC 2778075. PMID 19907493.
  12. ^ Keim, Brandon (11 November 2009). "Human-Chimp Gene Comparison Hints at Roots of Language". Wired. Retrieved 5 December 2014.
  13. ^ Voineagu, Irina; Wang, Xinchen; Johnston, Patrick; Lowe, Jennifer K.; Tian, Yuan; Horvath, Steve; Mill, Jonathan; Cantor, Rita M.; Blencowe, Benjamin J.; Geschwind, Daniel H. (25 May 2011). "Transcriptomic analysis of autistic brain reveals convergent molecular pathology". Nature. 474 (7351): 380–384. doi:10.1038/nature10110. PMC 3607626. PMID 21614001.
  14. ^ "Autistic brains' 'genes differ'". BBC News. 25 May 2011. Retrieved 5 December 2014.
  15. ^ Hotz, Robert Lee (5 March 2002). "Left-Handers Are Found to Have Different Brains". Los Angeles Times. Retrieved 6 December 2014.
  16. ^ Klass, Perri (6 March 2011). "On the Left Hand, There Are No Easy Answers". New York Times. Retrieved 6 December 2014.
  17. ^ "Highly Cited Researchers List 2017 - Top Researchers Around the World". clarivate.com. Retrieved 8 October 2018.