Dess–Martin oxidation

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Dess–Martin oxidation
Named after Daniel Benjamin Dess
James Cullen Martin
Reaction type Organic redox reaction
Organic Chemistry Portal dess-martin-oxidation
RSC ontology ID RXNO:0000256

The Dess–Martin oxidation is an organic reaction for the oxidation of primary alcohols to aldehydes and secondary alcohols to ketones using Dess-Martin periodinane.[1] It is named after the American chemists Daniel Benjamin Dess and James Cullen Martin who developed the periodinane reagent in 1983.

Reaction scheme

The acceleration of the Dess–Martin oxidation reaction using water has been shown by Meyer and Schreiber.[2]

See also[edit]


  1. ^ Dess, Daniel B.; Martin, James C. (1983). "Readily accessible 12-I-5 oxidant for the conversion of primary and secondary alcohols to aldehydes and ketones". J. Org. Chem. 48 (22): 4155–4156. doi:10.1021/jo00170a070. 
  2. ^ Meyer, Stephanie D.; Schreiber, Stuart L. (1994). "Acceleration of the Dess-Martin Oxidation by Water". J. Org. Chem. 59 (24): 7549–7552. doi:10.1021/jo00103a067.