In 1642, Wooster enters the record as one of the first colonists of Milford, Connecticut. In 1651, he received permission to settle an area known as "Paugusset". In 1669, he was appointed constable of Paugusset.
Edward Wooster died on July 8, 1689. Wooster's tombstone in Derby states:
In memory of Edward Wooster 1622–1689
The first permanent settler in Derby — 1651 —
"The wilderness and the solitary place shall be glad for them
and the desert shall rejoice and blossom as the rose"