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FCER1G

From Wikipedia, the free encyclopedia
FCER1G
Identifiers
AliasesFCER1G, FCRG, Fc fragment of IgE receptor Ig, Fc epsilon receptor Ig
External IDsOMIM: 147139; MGI: 95496; HomoloGene: 3029; GeneCards: FCER1G; OMA:FCER1G - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004106

NM_010185

RefSeq (protein)

NP_004097

NP_034315

Location (UCSC)Chr 1: 161.22 – 161.22 MbChr 1: 171.06 – 171.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide is gamma chain of high affinity IgE receptor. This protein is encoded by the FCER1G gene in humans.[5]

Function

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The high affinity IgE receptor, FcεRI, is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000158869Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058715Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.