FEZ2

FEZ2
Identifiers
Aliases	FEZ2, HUM3CL, fasciculation and elongation protein zeta 2
External IDs	OMIM: 604826; MGI: 2675856; HomoloGene: 3742; GeneCards: FEZ2; OMA:FEZ2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	36,646,087 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	78,725,581 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; secondary oocyte; ; Skeletal muscle tissue of rectus abdominis; ; Skeletal muscle tissue of biceps brachii; ; thoracic diaphragm; ; deltoid muscle; ; parietal pleura; ; muscle of thigh; ; visceral pleura; ; Brodmann area 23;
	Top expressed in
	epithelium of lens; ; sternocleidomastoid muscle; ; muscle of thigh; ; triceps brachii muscle; ; retinal pigment epithelium; ; right ventricle; ; temporal muscle; ; quadriceps femoris muscle; ; digastric muscle; ; gastrocnemius muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; axon;
Biological process	signal transduction; nervous system development; negative regulation of autophagosome assembly; axon guidance;
	Sources:Amigo / QuickGO
Orthologs
	9637
	225020
	ENSG00000171055
	ENSMUSG00000056121
	Q9UHY8
	Q6TYB5
	NM_001042548; NM_005102
	NM_001285940; NM_001285946; NM_001285949; NM_199448; NM_001360407
	NP_001036013; NP_005093
	NP_001272869; NP_001272875; NP_001272878; NP_955519; NP_001347336
	Wikidata
View/Edit Human	View/Edit Mouse

Fasciculation and elongation protein zeta-2 is a protein that in humans is encoded by the FEZ2 gene.^[5]^[6]

Interactions

FEZ2 has been shown to interact with Protein kinase Mζ.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171055 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056121 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bloom L, Horvitz HR (May 1997). "The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation". Proc Natl Acad Sci U S A. 94 (7): 3414–9. Bibcode:1997PNAS...94.3414B. doi:10.1073/pnas.94.7.3414. PMC 20384. PMID 9096408.
^ "Entrez Gene: FEZ2 fasciculation and elongation protein zeta 2 (zygin II)".
^ Fujita, Toshitsugu; Ikuta Junko; Hamada Juri; Okajima Toshihide; Tatematsu Kenji; Tanizawa Katsuyuki; Kuroda Shun'ichi (Jan 2004). "Identification of a tissue-non-specific homologue of axonal fasciculation and elongation protein zeta-1". Biochem. Biophys. Res. Commun. 313 (3). United States: 738–44. doi:10.1016/j.bbrc.2003.12.006. ISSN 0006-291X. PMID 14697253. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)