FOLR2

FOLR2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4KMY, 4KMZ, 4KN0, 4KN1, 4KN2
Identifiers
Aliases	FOLR2, BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3, folate receptor beta, FRbeta, FOLR1
External IDs	OMIM: 136425; MGI: 95569; HomoloGene: 627; GeneCards: FOLR2; OMA:FOLR2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	72,221,950 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	101,506,401 bp
RNA expression pattern
	Top expressed in
	gallbladder; ; right coronary artery; ; synovial joint; ; lymph node; ; synovial membrane; ; gonad; ; pericardium; ; decidua; ; testicle; ; rectum;
	Top expressed in
	stroma of bone marrow; ; lip; ; ankle joint; ; white adipose tissue; ; esophagus; ; muscle of thigh; ; ankle; ; mammary gland; ; subcutaneous adipose tissue; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	methotrexate binding; folic acid binding; folic acid receptor activity; signaling receptor activity;
Cellular component	cell surface; anchored component of membrane; anchored component of external side of plasma membrane; membrane; extracellular region; plasma membrane;
Biological process	inflammatory response; receptor-mediated endocytosis; positive regulation of cell population proliferation; monocyte chemotaxis; cellular response to folic acid; folic acid metabolic process; folic acid transport; folate import across plasma membrane; cell adhesion; fusion of sperm to egg plasma membrane involved in single fertilization; sperm-egg recognition;
	Sources:Amigo / QuickGO
Orthologs
	2350
	14276
	ENSG00000165457
	ENSMUSG00000032725
	P14207
	Q05685
	NM_000803; NM_001113534; NM_001113535; NM_001113536
	NM_008035; NM_001303231; NM_001303239
	NP_000794; NP_001107006; NP_001107007; NP_001107008
	NP_001290160; NP_001290168; NP_032061
	Wikidata
View/Edit Human	View/Edit Mouse

Folate receptor beta is a protein that in humans is encoded by the FOLR2 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000165457 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032725 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kawasaki K, Fearnhead RW (Sep 1975). "On the relationship between tetracycline and the incremental lines in dentine". J Anat. 119 (Pt 1): 49–59. PMC 1231614. PMID 1133088.
^ van Heyningen V, Little PF (May 1995). "Report of the fourth international workshop on human chromosome 11 mapping 1994". Cytogenet Cell Genet. 69 (3–4): 127–58. doi:10.1159/000133953. PMID 7698003.
^ "Entrez Gene: FOLR2 folate receptor 2 (fetal)".

References

Further reading