FXYD2

FXYD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MKV
Identifiers
Aliases	FXYD2, ATP1G1, HOMG2, FXYD domain containing ion transport regulator 2
External IDs	OMIM: 601814 MGI: 1195260 HomoloGene: 86992 GeneCards: FXYD2
Gene location (Human)
Chr.	Chromosome 11 (human)
End	117,828,698 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	45,321,576 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; gallbladder; ; islet of Langerhans; ; kidney; ; minor salivary glands; ; right lobe of liver; ; left uterine tube; ; lymph node; ; spleen; ; smooth muscle tissue;
	Top expressed in
	kidney; ; proximal tubule; ; submandibular gland; ; yolk sac; ; parotid gland; ; thymus; ; distal tubule; ; Ascending limb of loop of Henle; ; inner renal medulla; ; thick ascending limb of loop of Henle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transporter activity; ion channel activity; P-type sodium:potassium-exchanging transporter activity; sodium channel regulator activity; ion channel regulator activity;
Cellular component	integral component of membrane; membrane; plasma membrane; extracellular exosome; integral component of plasma membrane; sodium:potassium-exchanging ATPase complex; basolateral plasma membrane; intracellular membrane-bounded organelle;
Biological process	regulation of cardiac conduction; sodium ion transport; sodium ion export across plasma membrane; ion transport; potassium ion transport; ion transmembrane transport; potassium ion import across plasma membrane; establishment or maintenance of transmembrane electrochemical gradient; regulation of cell growth; regulation of cell population proliferation; regulation of sodium ion transmembrane transporter activity; transport; regulation of ion transport;
	Sources:Amigo / QuickGO
Orthologs
	486
	11936
	ENSG00000137731
	ENSMUSG00000059412
	P54710
	Q04646
	NM_021603; NM_001127489; NM_001680
	NM_007503; NM_052823
	NP_001671; NP_067614
	NP_031529; NP_439888; NP_001391593
	Wikidata
View/Edit Human	View/Edit Mouse

Sodium/potassium-transporting ATPase gamma chain is a protein that in humans is encoded by the FXYD2 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137731 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000059412 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kim JW, Lee Y, Lee IA, Kang HB, Choe YK, Choe IS (Apr 1997). "Cloning and expression of human cDNA encoding Na+, K(+)-ATPase gamma-subunit". Biochim Biophys Acta. 1350 (2): 133–5. doi:10.1016/S0167-4781(96)00219-9. PMID 9048881.
^ Meij IC, Saar K, van den Heuvel LP, Nuernberg G, Vollmer M, Hildebrandt F, Reis A, Monnens LA, Knoers NV (Mar 1999). "Hereditary isolated renal magnesium loss maps to chromosome 11q23". Am J Hum Genet. 64 (1): 180–8. doi:10.1086/302199. PMC 1377716. PMID 9915957.
^ "Entrez Gene: FXYD2 FXYD domain containing ion transport regulator 2".

References

Further reading