GDI2

GDI2
Identifiers
Aliases	GDI2, HEL-S-46e, RABGDIB, GDP dissociation inhibitor 2
External IDs	OMIM: 600767; MGI: 99845; HomoloGene: 37488; GeneCards: GDI2; OMA:GDI2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	5,842,132 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	3,617,871 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; mucosa of ileum; ; mucosa of sigmoid colon; ; corpus epididymis; ; trabecular bone; ; visceral pleura; ; parietal pleura; ; secondary oocyte; ; epithelium of nasopharynx; ; oral cavity;
	Top expressed in
	saccule; ; otic placode; ; renal corpuscle; ; maxillary prominence; ; condyle; ; fossa; ; medullary collecting duct; ; internal carotid artery; ; ureter; ; external carotid artery;
	More reference expression data
	n/a
Gene ontology
Molecular function	Rab GDP-dissociation inhibitor activity; GTPase activator activity; small GTPase binding; protein binding; GDP-dissociation inhibitor activity; RNA binding;
Cellular component	cytoplasm; vesicle; cytosol; membrane; focal adhesion; extracellular exosome; extracellular region; secretory granule lumen; azurophil granule lumen; Golgi apparatus; synapse;
Biological process	positive regulation of GTPase activity; protein transport; regulation of catalytic activity; regulation of small GTPase mediated signal transduction; vesicle-mediated transport; signal transduction; small GTPase mediated signal transduction; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	2665
	14569
	ENSG00000057608
	ENSMUSG00000021218
	P50395; Q5SX91
	Q61598
	NM_001494; NM_001115156
	NM_008112
	NP_001108628; NP_001485
	NP_032138
	Wikidata
View/Edit Human	View/Edit Mouse

Rab GDP dissociation inhibitor beta is a protein that in humans is encoded by the GDI2 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000057608 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021218 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sedlacek Z, Munstermann E, Mincheva A, Lichter P, Poustka A (Feb 1998). "The human rab GDI beta gene with long retroposon-rich introns maps to 10p15 and its pseudogene to 7p11-p13". Mamm Genome. 9 (1): 78–80. doi:10.1007/s003359900685. PMID 9434952.
^ "Entrez Gene: GDI2 GDP dissociation inhibitor 2".

References

Further reading