GUCA1B

GUCA1B
Identifiers
Aliases	GUCA1B, GCAP2, GUCA2, RP48, guanylate cyclase activator 1B, GCAP 2
External IDs	OMIM: 602275; MGI: 1194489; HomoloGene: 1586; GeneCards: GUCA1B; OMA:GUCA1B - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	42,194,956 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	47,703,892 bp
RNA expression pattern
	Top expressed in
	testicle; ; cerebellar hemisphere; ; granulocyte; ; right hemisphere of cerebellum; ; tibialis anterior muscle; ; gastrocnemius muscle; ; stromal cell of endometrium; ; tibial nerve; ; trabecular bone; ; right uterine tube;
	Top expressed in
	layer of retina; ; neural layer of retina; ; embryo; ; embryo; ; quadriceps femoris muscle; ; outer nuclear layer; ; islet of Langerhans; ; bone marrow; ; zone of skin; ; lens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; guanylate cyclase regulator activity; metal ion binding; calcium sensitive guanylate cyclase activator activity;
Cellular component	photoreceptor inner segment; membrane; plasma membrane; photoreceptor outer segment; photoreceptor disc membrane;
Biological process	phototransduction; response to stimulus; cell-cell signaling; positive regulation of guanylate cyclase activity; regulation of guanylate cyclase activity; receptor guanylyl cyclase signaling pathway; body fluid secretion; visual perception; regulation of rhodopsin mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2979
	107477
	ENSG00000112599
	ENSMUSG00000023979
	Q9UMX6
	Q8VBV8
	NM_002098
	NM_146079
	NP_002089
	NP_666191
	Wikidata
View/Edit Human	View/Edit Mouse

Guanylyl cyclase-activating protein 2 is an enzyme that in humans is encoded by the GUCA1B gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112599 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023979 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Surguchov A, Bronson JD, Banerjee P, Knowles JA, Ruiz C, Subbaraya I, Palczewski K, Baehr W (Apr 1997). "The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1)". Genomics. 39 (3): 312–22. doi:10.1006/geno.1996.4513. PMID 9119368.
^ "Entrez Gene: GUCA1B guanylate cyclase activator 1B (retina)".

External links

GeneReviews/NCBI/NIH/UW entry on Retinitis Pigmentosa Overview

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This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112599 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000023979 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9119368-5] Surguchov A, Bronson JD, Banerjee P, Knowles JA, Ruiz C, Subbaraya I, Palczewski K, Baehr W (Apr 1997). "The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1)". Genomics. 39 (3): 312–22. doi:10.1006/geno.1996.4513. PMID 9119368.

[entrez-6] "Entrez Gene: GUCA1B guanylate cyclase activator 1B (retina)".

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References

Further reading

External links