He was the son of John Marshall, an Irish gentleman who was knighted in 1643 for his service during the Battle of Rocroi. In 1677 Mareschal moved to Paris, where he worked as a surgical assistant. From 1684 onward, he worked at the Hôpital de la Charité, where in 1688 he became master-surgeon, later earning the title of chief-surgeon (1692).
He was first-surgeon to Louis XIV and then to Louis XV. In 1723 he was awarded the Ordre de Saint-Michel for successfully treating the Infanta of Spain. In 1731, with François Gigot de la Peyronie (1678–1747), he founded the Académie Royale de Chirurgie. He is credited with making improvements in lithotomical surgery.
- Peumery, JJ (1996). "Georges Mareschal (1658-1736) fondateur de l'Académie de chirurgie" [Georges Mareschal (1658-1736) the founder of the Académie de Chirurgie]. Histoire des sciences médicales (in French). 30 (3): 323–31. PMID 11624982.
- NCBI, Georges Mareschal (1658-1736) the founder of the Académie de Chirurgie Hist Sci Med. 1996;30(3):323-31. PMID 11624982
- Near relations of Georges Mareschal, first surgeon of Louis XIV and Louis XV (1658-1736 Vesalius. 1997 Dec;3(2):85-90. PMID 11619882
- Archives du Pas-de-Calais April 8, 1658: born in Calais surgeon Georges Mareschal
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