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Geum japonicum

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Geum japonicum
Scientific classification
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G. japonicum
Binomial name
Geum japonicum
Varieties

G. j. var. Thunberg

Geum japonicum, known as Asian herb bennet,[1] is a yellow-flowering perennial plant native to North America and East Asia, especially Japan. It may be synonymous with Geum macrophyllum, the North American flower. As a traditional herbal remedy it is known as an astringent and used in poultices.[2] However, in recent years, the Thunberg variant has received attention for other possible medical uses.

With regard to muscular recovery, an extract has been found to help muscles recover following "severe injury",[3] to reduce myocardial infarct size by 35–45% when administered following a heart attack,[4] and to inhibit apoptosis.[5] It also has possible anti-viral properties,[6] including action against HIV [7] and HSV.[8] Action against tumors has also been noted.[9]

References

  1. ^ English Names for Korean Native Plants (PDF). Pocheon: Korea National Arboretum. 2015. p. 480. ISBN 978-89-97450-98-5. Archived from the original (PDF) on 25 May 2017. Retrieved 4 January 2017 – via Korea Forest Service. {{cite book}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  2. ^ Geum japonicum. Plants for a Future. Retrieved April 27, 2012, from http://www.pfaf.org/user/Plant.aspx?LatinName=Geum+japonicum
  3. ^ Cheng et al. (2006). A new function of a previously isolated compound that stimulates activation and differentiation of myogenic precursor cells leading to efficient myofiber regeneration and muscle repair. Int J Biochem Cell Biol. 2006;38(7):1123–33. PMID 16431151
  4. ^ Li et al. (2006). Repair of infarcted myocardium by an extract of Geum japonicum with dual effects on angiogenesis and myogenesis. Clin Chem. 2006 Aug;52(8):1460-8. PMID 16873297
  5. ^ Gu et al. (2007). Neovascularization of ischemic myocardium by newly isolated tannins prevents cardiomyocyte apoptosis and improves cardiac function. Mol Med. 2006 Nov–Dec;12(11–12):275-83. PMID 17380192
  6. ^ Kageyama et al. (1996). Potent activity of the extract of Geum japonicum Thunb. For the prophylaxis of cytomegalovirus infection in AIDS patients. Int Conf AIDS. 1996 Jul 7–12; 11: 65. Retrieved August 8, 2008, from http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102217030.html
  7. ^ Xu, Ming, Dong, & Butt. (2000). A new anti-HIV triterpene from Geum japonicum. Chem Pharm Bull 2000 Sep;48(9):1367-9. PMID 10993241
  8. ^ Kurokawa et al. (1998). Purification and characterization of eugeniin as an anti-herpesvirus compound from Geum japonicum and Syzygium aromaticum. J Pharmacol Exp Ther. 1998 Feb;284(2):728-35. PMID 9454821
  9. ^ Heo et al. (2008). A fraction of methylene chloride from Geum japonicum Thunberg inhibits tumor metastatic and angiogenic potential. Oncol Rep. 2008 Jun;19(6):1399-403. PMID 18497943