In enzymology, a glucose-6-phosphate 1-epimerase (EC 126.96.36.199) is an enzyme that catalyzes the chemical reaction
- alpha-D-glucose 6-phosphate beta-D-glucose 6-phosphate
Hence, this enzyme has one substrate, alpha-D-glucose 6-phosphate, and one product, beta-D-glucose 6-phosphate.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is D-glucose-6-phosphate 1-epimerase. This enzyme participates in glycolysis / gluconeogenesis.
As of late 2013, 3 structures have been solved for this class of enzymes, with PDB accession codes 2CIQ, 2CIR, and 2CIS.