HAUS3

HAUS3
Identifiers
Aliases	HAUS3, C4orf15, IT1, dgt3, HAUS augmin like complex subunit 3
External IDs	OMIM: 613430; MGI: 2387633; HomoloGene: 75209; GeneCards: HAUS3; OMA:HAUS3 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	2,242,276 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	34,326,871 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; gonad; ; Achilles tendon; ; ventricular zone; ; oral cavity; ; visceral pleura; ; parietal pleura; ; ganglionic eminence; ; bone marrow; ; skin of thigh;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; zygote; ; primitive streak; ; maxillary prominence; ; mandibular prominence; ; abdominal wall; ; thymus; ; epiblast; ; tail of embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; molecular function;
Cellular component	microtubule cytoskeleton; cytoplasm; microtubule organizing center; centrosome; microtubule; HAUS complex; cytoskeleton; mitochondrion; nucleoplasm; cytosol; spindle; intercellular bridge; mitotic spindle;
Biological process	spindle assembly; cell cycle; cell division; G2/M transition of mitotic cell cycle; ciliary basal body-plasma membrane docking; centrosome cycle; regulation of G2/M transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	79441
	231123
	ENSG00000214367
	ENSMUSG00000079555
	Q68CZ6
	Q8QZX2
	NM_024511; NM_001303143
	NM_146159
	NP_001290072; NP_078787
	NP_666271
	Wikidata
View/Edit Human	View/Edit Mouse

HAUS augmin-like complex subunit 3 is a protein that in humans is encoded by the HAUS3 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000214367 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000079555 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: HAUS augmin-like complex".
^ Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Hegemann B, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L (May 2009). "HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity". Curr. Biol. 19 (10): 816–26. doi:10.1016/j.cub.2009.04.033. PMID 19427217.

Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Uehara R, Nozawa RS, Tomioka A, et al. (2009). "The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells". Proc. Natl. Acad. Sci. U.S.A. 106 (17): 6998–7003. doi:10.1073/pnas.0901587106. PMC 2668966. PMID 19369198.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.

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