HIST1H1E

H1-4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3TZD, 5JJZ
Identifiers
Aliases	H1-4, histone cluster 1, H1e, H1.4, H1E, H1F4, H1s-4, dJ221C16.5, histone cluster 1 H1 family member e, RMNS, HIST1H1E, H1.4 linker histone, cluster member
External IDs	OMIM: 142220 MGI: 1931527 HomoloGene: 130534 GeneCards: H1-4
Gene location (Human)
Chr.	Chromosome 6 (human)
End	26,157,115 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	23,806,541 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; sural nerve; ; bone marrow cells; ; corpus callosum; ; secondary oocyte; ; thymus; ; islet of Langerhans; ; blood; ; internal globus pallidus; ; skin of abdomen;
	Top expressed in
	ascending aorta; ; aortic valve; ; morula; ; supraoptic nucleus; ; blastocyst; ; lens; ; neural tube; ; proximal tubule; ; yolk sac; ; spermatid;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; chromatin DNA binding; protein binding; RNA binding; nucleotide binding; double-stranded DNA binding; calcium ion binding; ATP binding; GTP binding; AMP binding; dATP binding; ADP binding; nucleosomal DNA binding;
Cellular component	nucleosome; extracellular exosome; nucleus; chromosome;
Biological process	regulation of transcription by RNA polymerase II; histone H3-K4 trimethylation; nucleosome assembly; negative regulation of transcription by RNA polymerase II; histone H3-K27 trimethylation; regulation of transcription, DNA-templated; chromosome condensation; negative regulation of DNA recombination;
	Sources:Amigo / QuickGO
Orthologs
	3008
	50709
	ENSG00000168298
	ENSMUSG00000051627
	P10412
	P43274
	NM_005321
	NM_015787
	NP_005312; NP_005312.1
	NP_056602
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H1.4 is a protein that in humans is encoded by the HIST1H1E gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168298 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051627 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Albig W, Kardalinou E, Drabent B, Zimmer A, Doenecke D (Nov 1991). "Isolation and characterization of two human H1 histone genes within clusters of core histone genes". Genomics. 10 (4): 940–8. doi:10.1016/0888-7543(91)90183-F. PMID 1916825.
^ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics. 80 (5): 487–98. doi:10.1016/S0888-7543(02)96850-3. PMID 12408966.
^ "Entrez Gene: HIST1H1E histone cluster 1, H1e".

References

Further reading