This article relies largely or entirely on a single source. (January 2015)
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Most heart tumors begin with myxomas, fibromas, rhabdomyomas, and hamartomas, although malignant sarcomas (such as angiosarcoma or cardiac sarcoma) have been known to occur. In a study of 12,487 autopsies performed in Hong Kong seven cardiac tumors were found, most of which were benign. According to Mayo Clinic: "At Mayo Clinic, on average only one case of heart cancer is seen each year." In a study conducted in the Hospital of the Medical University of Vienna 113 primary cardiac tumour cases were identified in a time period of 15 years with 11 being malignant. The mean survival in the latter group of patients was found to be 26.2 ± 9.8 months.
Primary malignant cardiac tumors (PMCTs) are even more rare. The most recent published study about PMCTs used the Surveillance, Epidemiology and End-Results (SEER) Cancer Registry to study 497 patients with PMCTs who were diagnosed during 2000-201 in the United States. Most cases were angiosarcomas (27.3%) with an incidence of 0.107 per 1,000,000 person-years and Non- Hodgkin's lymphomas [NHL] (26.9%), with an incidence of 0.108 per 1,000,000 person-years. The incidence rate of NHL increased significantly over the study period, but the incidence of cardiac angiosarcomas did not. The overall survival of NHL wa found to be significantly better than angiosarcomas. 
Another previous study using the Surveillance, Epidemiology and End-Results (SEER) Cancer Registry from 1973–2011 found 551 cases of PMCTs, with an incidence of 34 cases per million persons. The study also found that the incidence has doubled over the past four decades. The associated mortality was very high, with only 46% of patients alive after one year. Sarcomas and mesotheliomas had the worst survival, while lymphomas had better survival. When compared with extracardiac tumors, PMCTs had worse survival.
- Catherine of Aragon's candidate cause of death was heart cancer.
- Eric Carr, drummer of the rock band Kiss, died of heart cancer.
- John Brim, blues musician and original writer of "Ice Cream Man", later covered by Van Halen.
- Alexander Belov, Soviet basketball player.
- Moynihan, Timothy J. (2015-03-25). "Heart cancer: Is there such a thing?". MayoClinic.com. Retrieved 2015-06-01.
- Habertheuer A, Laufer G, Wiedemann D, Andreas M, Ehrlich M, Rath C, Kocher A (April 2015). "Primary cardiac tumors on the verge of oblivion: a European experience over 15 years". J Cardiothorac Surg. 10: 56. doi:10.1186/s13019-015-0255-4. PMC . PMID 25928192.
- Anas M. Saad, Abdelrahman Ibrahim Abushouk, Muneer J. Al-Husseini, Sami Salahia, Anas Alrefai, Ahmed M Afifi, Mohamed M. Abdel-Daim , Characteristics, Survival and Incidence Rates and Trends of Primary Cardiac Malignancies in the United States. Cardiovascular Pthology, DOI: https://doi.org/10.1016/j.carpath.2017.12.001
- Oliveira et al. Circulation. 2015; 132: 2395–2402 doi:10.1161/CIRCULATIONAHA.115.016418.
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