IFIT2

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IFIT2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases IFIT2, G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, P54, cig42, interferon induced protein with tetratricopeptide repeats 2
External IDs MGI: 99449 HomoloGene: 1187 GeneCards: IFIT2
Gene location (Human)
Chromosome 10 (human)
Chr. Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for IFIT2
Genomic location for IFIT2
Band 10q23.31 Start 89,283,694 bp[1]
End 89,309,276 bp[1]
RNA expression pattern
PBB GE IFIT2 217502 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001547

NM_008332
NM_001355262

RefSeq (protein)

NP_001538

NP_032358
NP_001342191

Location (UCSC) Chr 10: 89.28 – 89.31 Mb Chr 19: 34.55 – 34.58 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interferon-induced protein with tetratricopeptide repeats 2 or IFIT2 is a protein found in humans which is encoded by the IFIT2 gene.[5][6][7]

Clinical significance[edit]

IFIT2 may play a role in prevention of tumor progression.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119922 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045932 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Wathelet MG, Szpirer J, Nols CB, Clauss IM, De Wit L, Islam MQ, Levan G, Horisberger MA, Content J, Szpirer C (Nov 1988). "Cloning and chromosomal location of human genes inducible by type I interferon". Somat Cell Mol Genet. 14 (5): 415–26. doi:10.1007/BF01534709. PMID 3175763. 
  6. ^ Wathelet MG, Clauss IM, Content J, Huez GA (Jun 1988). "The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family". FEBS Lett. 231 (1): 164–71. doi:10.1016/0014-5793(88)80724-5. PMID 3360121. 
  7. ^ "Entrez Gene: IFIT2 interferon-induced protein with tetratricopeptide repeats 2". 
  8. ^ Lai KC, Chang KW, Liu CJ, Kao SY, Lee TC (2008). "IFN-induced protein with tetratricopeptide repeats 2 inhibits migration activity and increases survival of oral squamous cell carcinoma". Mol. Cancer Res. 6 (9): 1431–9. doi:10.1158/1541-7786.MCR-08-0141. PMID 18819931. 

Further reading[edit]