IGF2BP3

IGF2BP3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2E44
Identifiers
Aliases	IGF2BP3, CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3, insulin like growth factor 2 mRNA binding protein 3
External IDs	OMIM: 608259; MGI: 1890359; HomoloGene: 4773; GeneCards: IGF2BP3; OMA:IGF2BP3 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	23,470,491 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	49,191,891 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; amniotic fluid; ; buccal mucosa cell; ; placenta; ; embryo; ; sperm; ; ventricular zone; ; ganglionic eminence; ; monocyte; ; cartilage tissue;
	Top expressed in
	primitive streak; ; tail of embryo; ; mandibular prominence; ; maxillary prominence; ; genital tubercle; ; somite; ; internal carotid artery; ; medullary collecting duct; ; abdominal wall; ; epithelium of small intestine;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	mRNA 5'-UTR binding; protein binding; translation regulator activity; mRNA 3'-UTR binding; nucleic acid binding; RNA binding;
Cellular component	nucleus; cytoplasm; cytosol;
Biological process	anatomical structure morphogenesis; negative regulation of translation; mRNA transport; protein biosynthesis; regulation of translation; regulation of mRNA stability; transport;
	Sources:Amigo / QuickGO
Orthologs
	10643
	140488
	ENSG00000136231
	ENSMUSG00000029814
	O00425
	Q9CPN8
	NM_006547
	NM_023670
	NP_006538
	NP_076159
	Wikidata
View/Edit Human	View/Edit Mouse

Insulin-like growth factor 2 mRNA-binding protein 3 is a protein that in humans is encoded by the IGF2BP3 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136231 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029814 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nielsen J, Christiansen J, Lykke-Andersen J, Johnsen AH, Wewer UM, Nielsen FC (Feb 1999). "A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development". Mol Cell Biol. 19 (2): 1262–70. PMC 116055. PMID 9891060.
^ Mueller-Pillasch F, Lacher U, Wallrapp C, Micha A, Zimmerhackl F, Hameister H, Varga G, Friess H, Buchler M, Beger HG, Vila MR, Adler G, Gress TM (Jul 1997). "Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein". Oncogene. 14 (22): 2729–33. doi:10.1038/sj.onc.1201110. PMID 9178771.
^ "Entrez Gene: IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3".