IK (gene)

IK
Identifiers
Aliases	IK, CSA2, RED, IK cytokine, down-regulator of HLA II, RER, IK cytokine
External IDs	OMIM: 600549; MGI: 1345142; HomoloGene: 36193; GeneCards: IK; OMA:IK - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	140,662,480 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	36,890,692 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; bronchial epithelial cell; ; right uterine tube; ; sural nerve; ; Achilles tendon; ; olfactory zone of nasal mucosa; ; epithelium of nasopharynx; ; left testis; ; right testis; ; ganglionic eminence;
	Top expressed in
	genital tubercle; ; tail of embryo; ; retinal pigment epithelium; ; Paneth cell; ; ciliary body; ; fossa; ; condyle; ; iris; ; supraoptic nucleus; ; Epithelium of choroid plexus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; identical protein binding;
Cellular component	nuclear speck; nuclear chromosome; mitotic spindle pole; spindle pole; nucleoplasm; spliceosomal complex; chromosome; cytoplasm; cytoskeleton; nucleus; U2-type precatalytic spliceosome;
Biological process	mitotic cell cycle; mitotic spindle assembly checkpoint signaling; protein localization to kinetochore; mRNA processing; RNA splicing; viral process; mRNA splicing, via spliceosome;
	Sources:Amigo / QuickGO
Orthologs
	3550
	24010
	ENSG00000113141
	ENSMUSG00000024474
	Q13123; Q95HA6
	Q9Z1M8
	NM_006083
	NM_011879
	NP_006074; NP_006074.2
	NP_036009
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Red is a protein that in humans is encoded by the IK gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113141 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024474 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Krief P, Augery-Bourget Y, Plaisance S, Merck MF, Assier E, Tanchou V, Billard M, Boucheix C, Jasmin C, Azzarone B (Dec 1994). "A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization". Oncogene. 9 (12): 3449–56. PMID 7970704.
^ "Entrez Gene: IK IK cytokine, down-regulator of HLA II".