IMMT

IMMT
Identifiers
Aliases	IMMT, HMP, MINOS2, P87, P87/89, P89, PIG52, Mic60, PIG4, inner membrane mitochondrial protein, MICOS60, mitofilin
External IDs	OMIM: 600378; MGI: 1923864; HomoloGene: 38234; GeneCards: IMMT; OMA:IMMT - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	86,195,472 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	71,854,372 bp
RNA expression pattern
	Top expressed in
	left ventricle; ; gastrocnemius muscle; ; apex of heart; ; right auricle; ; biceps brachii; ; right ventricle; ; Skeletal muscle tissue of biceps brachii; ; gonad; ; right adrenal cortex; ; body of tongue;
	Top expressed in
	myocardium of ventricle; ; tail of embryo; ; genital tubercle; ; right kidney; ; right ventricle; ; cardiac muscles; ; soleus muscle; ; muscle of thigh; ; digastric muscle; ; brown adipose tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	integral component of membrane; mitochondrial inner membrane; myelin sheath; MICOS complex; membrane; mitochondrion;
Biological process	cristae formation; mitochondrial calcium ion homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	10989
	76614
	ENSG00000132305
	ENSMUSG00000052337
	Q16891
	Q8CAQ8
	NM_001100169; NM_001100170; NM_006839
NM_001253681; NM_001253686; NM_001253687; NM_001253688; NM_001253689;
	NM_029673; NM_001362134; NM_001362136; NM_001362137; NM_001362138
	NP_001093639; NP_001093640; NP_006830
NP_001240610; NP_001240615; NP_001240616; NP_001240617; NP_001240618;
	NP_083949; NP_001349063; NP_001349065; NP_001349066; NP_001349067
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial inner membrane protein is a protein that in humans is encoded by the IMMT gene.^[5]^[6]^[7]

Template:PBB Summary

Interactions

IMMT has been shown to interact with BAT2.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132305 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052337 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Gieffers C, Korioth F, Heimann P, Ungermann C, Frey J (Jun 1997). "Mitofilin is a transmembrane protein of the inner mitochondrial membrane expressed as two isoforms". Exp Cell Res. 232 (2): 395–9. doi:10.1006/excr.1997.3539. PMID 9168817.
^ Icho T, Ikeda T, Matsumoto Y, Hanaoka F, Kaji K, Tsuchida N (Aug 1994). "A novel human gene that is preferentially transcribed in heart muscle". Gene. 144 (2): 301–6. doi:10.1016/0378-1119(94)90394-8. PMID 8039717.
^ "Entrez Gene: IMMT inner membrane protein, mitochondrial (mitofilin)".
^ Lehner, Ben; Semple Jennifer I; Brown Stephanie E; Counsell Damian; Campbell R Duncan; Sanderson Christopher M (Jan 2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1). United States: 153–67. doi:10.1016/S0888-7543(03)00235-0. ISSN 0888-7543. PMID 14667819. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

Interactions

References

Further reading