KIF2C

KIF2C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HEH, 4UBF, 4Y05
Identifiers
Aliases	KIF2C, CT139, KNSL6, MCAK, kinesin family member 2C
External IDs	OMIM: 604538; MGI: 1921054; HomoloGene: 21355; GeneCards: KIF2C; OMA:KIF2C - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	44,767,767 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	117,039,836 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; ventricular zone; ; right testis; ; left testis; ; sperm; ; embryo; ; ganglionic eminence; ; gonad; ; testicle; ; bone marrow;
	Top expressed in
	otic placode; ; seminiferous tubule; ; otic vesicle; ; primary oocyte; ; saccule; ; primitive streak; ; maxillary prominence; ; spermatid; ; endothelial cell of lymphatic vessel; ; mandibular prominence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; microtubule binding; microtubule plus-end binding; centromeric DNA binding; ATPase activity; protein binding; ATP binding; microtubule motor activity;
Cellular component	cytoplasm; membrane; kinesin complex; microtubule cytoskeleton; chromosome; microtubule plus-end; cytoplasmic microtubule; chromosome, centromeric region; cytoskeleton; microtubule; nucleus; kinetochore; nucleoplasm; centrosome; cytosol;
Biological process	antigen processing and presentation of exogenous peptide antigen via MHC class II; establishment or maintenance of microtubule cytoskeleton polarity; chromosome segregation; cell division; regulation of chromosome segregation; microtubule-based movement; cell cycle; microtubule depolymerization; mitotic metaphase plate congression; cell population proliferation; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; sister chromatid cohesion; metaphase plate congression; attachment of mitotic spindle microtubules to kinetochore; mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	11004
	73804
	ENSG00000142945
	ENSMUSG00000028678
	Q99661
	Q922S8
	NM_001297655; NM_001297656; NM_001297657; NM_006845
	NM_001290662; NM_134471
	NP_001284584; NP_001284585; NP_001284586; NP_006836
	NP_001277591; NP_608301
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000142945 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028678 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kim IG, Jun DY, Sohn U, Kim YH (Feb 1998). "Cloning and expression of human mitotic centromere-associated kinesin gene". Biochim Biophys Acta. 1359 (3): 181–6. doi:10.1016/s0167-4889(97)00103-1. PMID 9434124.
^ "Entrez Gene: KIF2C kinesin family member 2C".

References

Further reading