This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
^Ichimura T, Wakamiya-Tsuruta A, Itagaki C, Taoka M, Hayano T, Natsume T et al. (Apr 2002). "Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein". Biochemistry41 (17): 5566–72. doi:10.1021/bi015946f. PMID11969417.
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Ichimura T, Wakamiya-Tsuruta A, Itagaki C, Taoka M, Hayano T, Natsume T et al. (Apr 2002). "Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein". Biochemistry41 (17): 5566–72. doi:10.1021/bi015946f. PMID11969417.
Rahman A, Friedman DS, Goldstein LS (Jun 1998). "Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins". The Journal of Biological Chemistry273 (25): 15395–403. doi:10.1074/jbc.273.25.15395. PMID9624122.
Lamerdin JE, Stilwagen SA, Ramirez MH, Stubbs L, Carrano AV (Jun 1996). "Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes". Genomics34 (3): 399–409. doi:10.1006/geno.1996.0303. PMID8786141.