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Kinesin light chain 3
Symbols KLC3 ; KLC2; KLC2L; KLCt; KNS2B
External IDs OMIM601334 MGI1277971 HomoloGene14899 GeneCards: KLC3 Gene
Species Human Mouse
Entrez 147700 232943
Ensembl ENSG00000104892 ENSMUSG00000040714
UniProt Q6P597 Q91W40
RefSeq (mRNA) NM_145275 NM_001286038
RefSeq (protein) NP_803136 NP_001272967
Location (UCSC) Chr 19:
45.33 – 45.35 Mb
Chr 7:
19.39 – 19.4 Mb
PubMed search [1] [2]

Kinesin light chain 3 is a protein that in humans is encoded by the KLC3 gene.[1]


This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.[1]


KLC3 has been shown to interact with YWHAH.[2]


  1. ^ a b "Entrez Gene: KLC3 kinesin light chain 3". 
  2. ^ Ichimura T, Wakamiya-Tsuruta A, Itagaki C, Taoka M, Hayano T, Natsume T, Isobe T (Apr 2002). "Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein". Biochemistry 41 (17): 5566–72. doi:10.1021/bi015946f. PMID 11969417. 

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