Kinesin light chain 3 is a protein that in humans is encoded by the KLC3gene.
This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
Jin J, Smith FD, Stark C et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol.14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID15324660.CS1 maint: Explicit use of et al. (link)
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet.36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.CS1 maint: Explicit use of et al. (link)
Ichimura T, Wakamiya-Tsuruta A, Itagaki C et al. (2002). "Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein". Biochemistry41 (17): 5566–72. doi:10.1021/bi015946f. PMID11969417.CS1 maint: Explicit use of et al. (link)
Rahman A, Friedman DS, Goldstein LS (1998). "Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins". J. Biol. Chem.273 (25): 15395–403. doi:10.1074/jbc.273.25.15395. PMID9624122.
Lamerdin JE, Stilwagen SA, Ramirez MH et al. (1996). "Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes". Genomics34 (3): 399–409. doi:10.1006/geno.1996.0303. PMID8786141.CS1 maint: Explicit use of et al. (link)