KLK14

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KLK14
Identifiers
Aliases KLK14, KLK-L6, kallikrein related peptidase 14
External IDs MGI: 2447564 HomoloGene: 69348 GeneCards: KLK14
RNA expression pattern
PBB GE KLK14 220573 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001311182
NM_022046

NM_174866

RefSeq (protein)

NP_001298111.1
NP_071329.2

NP_777355.1

Location (UCSC) Chr 19: 51.08 – 51.08 Mb Chr 7: 43.69 – 43.7 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Kallikrein-14 is a protein that in humans is encoded by the KLK14 gene.[3][4][5]

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. An additional transcript variant has been described but its full length nature has not been determined.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, Stephan C, Talieri M, Yousef GM (Jun 2006). "A comprehensive nomenclature for serine proteases with homology to tissue kallikreins". Biol Chem. 387 (6): 637–41. doi:10.1515/BC.2006.082. PMID 16800724. 
  4. ^ Diamandis, Eleftherios P.; Deperthes, David; Lundwall, Åke (Jun 2006). "Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005". Biol Chem. 387 (6): 635–824. doi:10.1515/BC.2006.081. PMID 16800723. 
  5. ^ a b "Entrez Gene: KLK14 kallikrein-related peptidase 14". 

Further reading[edit]

External links[edit]

  • The MEROPS online database for peptidases and their inhibitors: S01.029