KRR1

KRR1
Identifiers
Aliases	KRR1, HRB2, RIP-1, small subunit processome component homolog, KRR1 small subunit processome component homolog
External IDs	OMIM: 612817; MGI: 1289274; HomoloGene: 5114; GeneCards: KRR1; OMA:KRR1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	75,511,636 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	111,824,337 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; oocyte; ; secondary oocyte; ; caput epididymis; ; gonad; ; tail of epididymis; ; mucosa of paranasal sinus; ; corpus epididymis; ; tonsil; ; islet of Langerhans;
	Top expressed in
	primitive streak; ; Paneth cell; ; genital tubercle; ; tail of embryo; ; fossa; ; abdominal wall; ; retinal pigment epithelium; ; condyle; ; ciliary body; ; vas deferens;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; nucleic acid binding; RNA binding;
Cellular component	cytoplasm; small-subunit processome; nucleolus; membrane; nucleus; intercellular bridge; nucleoplasm;
Biological process	ribosome biogenesis; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	11103
	52705
	ENSG00000111615
	ENSMUSG00000063334
	Q13601
	Q8BGA5
	NM_007043
	NM_178610
	NP_008974
	NP_848725
	Wikidata
View/Edit Human	View/Edit Mouse

KRR1 small subunit processome component homolog is a protein that in humans is encoded by the KRR1 gene.^[5]^[6]^[7]^[8]^[9]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111615 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000063334 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Epplen C, Epplen JT (Feb 1994). "Expression of (cac)n/(gtg)n simple repetitive sequences in mRNA of human lymphocytes". Hum Genet. 93 (1): 35–41. doi:10.1007/BF00218910. PMID 7505766.
^ Sasaki T, Toh-E A, Kikuchi Y (Oct 2000). "Yeast Krr1p Physically and Functionally Interacts with a Novel Essential Kri1p, and Both Proteins Are Required for 40S Ribosome Biogenesis in the Nucleolus". Mol Cell Biol. 20 (21): 7971–9. doi:10.1128/MCB.20.21.7971-7979.2000. PMC 86407. PMID 11027267.
^ Chan HY, Brogna S, O'Kane CJ (May 2001). "Dribble, the Drosophila KRR1p Homologue, Is Involved in rRNA Processing". Mol Biol Cell. 12 (5): 1409–19. doi:10.1091/mbc.12.5.1409. PMC 34593. PMID 11359931.
^ Gromadka R, Kaniak A, Slonimski PP, Rytka J (Aug 1996). "A novel cross-phylum family of proteins comprises a KRR1 (YCL059c) gene which is essential for viability of Saccharomyces cerevisiae cells". Gene. 171 (1): 27–32. doi:10.1016/0378-1119(96)00024-8. PMID 8675026.
^ "Entrez Gene: KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)".