KTTI is programmed by Program Director Misty Smith, who also serves as KTTI music director. Jeff and Misty also host "Jeff 'n Misty Mornings" weekdays from 6 to 10. The rest of the line-up includes Amy Cross on Mid-Day 10–2, Jenifer Grant in the Afternoon and the syndicated Whitney Allen at night. Kix Brooks hosts the "Kickin' it with Kix" show from 1am to 6am.
Recently, KTTI was voted Yuma's favorite radio station by readers of the Yuma Sun newspaper. This marked the 12th straight year the station was chosen as Yuma's best radio station. Jeff and Misty were voted Yuma best radio personalities for 2014.