LHX4

LHX4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3MMK
Identifiers
Aliases	LHX4, CPHD4, LIM homeobox 4
External IDs	OMIM: 602146; MGI: 101776; HomoloGene: 56497; GeneCards: LHX4; OMA:LHX4 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	180,278,984 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	155,627,430 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; sperm; ; secondary oocyte; ; testicle; ; right hemisphere of cerebellum; ; left testis; ; body of pancreas; ; rectum; ; right testis; ; stromal cell of endometrium;
	Top expressed in
	pineal gland; ; urethra; ; male urethra; ; serosa of urinary bladder; ; muscle layer of urethra; ; neural layer of retina; ; epithelium of male urethra; ; basal plate; ; rib; ; lamina propria of urinary bladder;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; metal ion binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; methyl-CpG binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding;
Cellular component	intracellular anatomical structure; nucleus;
Biological process	animal organ morphogenesis; medial motor column neuron differentiation; negative regulation of apoptotic process; regulation of transcription, DNA-templated; motor neuron axon guidance; transcription, DNA-templated; placenta development; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; neuron differentiation;
	Sources:Amigo / QuickGO
Orthologs
	89884
	16872
	ENSG00000121454
	ENSMUSG00000026468
	Q969G2
	P53776
	NM_033343
	NM_010712
	NP_203129
	NP_034842
	Wikidata
View/Edit Human	View/Edit Mouse

LIM/homeobox protein Lhx4 is a protein that in humans is encoded by the LHX4 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000121454 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026468 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Liu Y, Fan M, Yu S, Zhou Y, Wang J, Yuan J, Qiang B (Feb 2002). "cDNA cloning, chromosomal localization and expression pattern analysis of human LIM-homeobox gene LHX4". Brain Res. 928 (1–2): 147–155. doi:10.1016/S0006-8993(01)03243-7. PMID 11844481.
^ Machinis K, Pantel J, Netchine I, Leger J, Camand OJ, Sobrier ML, Dastot-Le Moal F, Duquesnoy P, Abitbol M, Czernichow P, Amselem S (Oct 2001). "Syndromic short stature in patients with a germline mutation in the LIM homeobox LHX4". Am J Hum Genet. 69 (5): 961–968. doi:10.1086/323764. PMC 1274372. PMID 11567216.
^ "Entrez Gene: LHX4 LIM homeobox 4".

References

Further reading